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1/6/2009
Tuesday morning
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| 1964 * Dr. Irving Selikoff publishes a study of asbestos workers in the Journal of the American Medical Association, proving that people who work with asbestos-containing materials have an abnormal incidence of asbestosis, lung cancer, and mesothelioma. Barry I. Castleman, Asbestos: Medical and Legal Aspects, 4th edition, Aspen Law and Business, Englewood Cliffs, NJ 1996, p.126 |
| >Carbone decided to use PCR to test 48 human mesotheliomas stored at the >NIH. He was stunned: 28 of them contained SV40. And the other 20? |
| Malignant mesothelioma is a cancer of the lining of the lung, usually induced by long years of exposure to asbestoes. Treatment is very unsatisfactory -- the disease is resistant to radiotherapy and poorly responsive to chemotherapy. In America, we try treatment with adriamycin, taxanes, or platinal but the odds are against success. In a managed care enviroment, I could understand a reluctance to offer anything more than drainage of the fluid, oxygen, and morphine. I dont think your fathers care is wrong since most treatments are likely to be futile. |
| >Studying 18- to 26-year-olds who probably had been exposed to the >contaminated vaccine, Fisher found a 19.6 percent greater incidence of the >two major brain cancers linked to SV40 when compared with the incidence in >people the same age who were not exposed. She also found 16.6 percent more >bone cancers and 178 percent more mesotheliomas among those exposed to the >vaccine. Did she control for tobacco use and other carcinogen exposure? Are the % differences with an incidence rate high enough to be statistically useful, or so small that a difference of one or two cases makes a big % diference? |
| >>> Gunisha Singh is a 46 year old Indian female with no significant past >>> medical history who presents for evaluation of a newly diagnosed right-sided >>> pleural malignant mesothelioma. >>> Mrs. Singh was in her usual excellent state of health until >>> approximately January 1996 when she noticed the onset of right neck, arm, >>> and shoulder discomfort gradually increasing in intensity. This was often >>> accompanied by a burning sensation in the distal arm and fingers on the >>> right side. At that time she was living in Hong Kong and was evaluated by a >>> neurosurgeon who felt that her symptoms were consistent with two herniated >>> cervical discs. The patient then came to the U.S. for evaluation by a >>> neurosurgeon at the University of California in San Francisco who felt that >>> she had cervical spondylosis with herniated disc. |
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