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1/6/2009
Tuesday morning
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| My mom, Gunisha Singh, was diagnosed about a month ago with Cancer--she has malignant mesothelioma, which is cancer of the inner chest cavity. This is a rare and mostly incurable form of cancer. Standard Treatment like chemotherapy and radiation therapy is not very effective against it, and by the time her particular cancer was diagnosed it was judged inoperable by Dr. M.S. Bains of the Memorial Sloane-Kettering Cancer Center in New York City. As far as we know, the only treatment that can potentially cure her is gene-therapy. Gene-therapy is on the cutting edge of cancer treatment; basically what doctors do is take an ordinary virus like the cold virus, fill it with "suicide genes" that will cause the cancer cells to self-destruct, and then inject the virus into the chest cavity. So far this treatment has been very successful. My mom was waiting in New York to get into a gene-therapy treatment program at t. |
| >Carbone was puzzled. Mesothelioma is a rare cancer. Few human cases were >reported before the 1950s, but its incidence had been increasing steadily, >reaching several thousand cases a year in the United States by 1988. This parallels, with a delay, the rise in use of tobacco, a strong carcinogen, and the exposure of persons to second-hand smoke. |
| 1964 * Dr. Irving Selikoff publishes a study of asbestos workers in the Journal of the American Medical Association, proving that people who work with asbestos-containing materials have an abnormal incidence of asbestosis, lung cancer, and mesothelioma. Barry I. Castleman, Asbestos: Medical and Legal Aspects, 4th edition, Aspen Law and Business, Englewood Cliffs, NJ 1996, p.126 |
| >Carbone decided to use PCR to test 48 human mesotheliomas stored at the >NIH. He was stunned: 28 of them contained SV40. And the other 20? |
| >>>>> Gunisha Singh is a 46 year old Indian female with no significant >>past >>>>> medical history who presents for evaluation of a newly diagnosed >>right-sided >>>>> pleural malignant mesothelioma. >>>>> Mrs. Singh was in her usual excellent state of health until >>>>> approximately January 1996 when she noticed the onset of right >>neck, arm, >>>>> and shoulder discomfort gradually increasing in intensity. This was >>often >>>>> accompanied by a burning sensation in the distal arm and fingers on >>the >>>>> right side. At that time she was living in Hong Kong and was >>evaluated by >>a >>>>> neurosurgeon who felt that her symptoms were consistent with two >>herniated >>>>> cervical discs. The patient then came to the U.S. for evaluation by &. |
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