 |
1/8/2009
Thursday morning
This topic is closed off and you will be taken directly to the website.
Topics taken from open source list. I hope you find this useful.
This site is for our clients only as an information resource.
| A case-control study on pleural malignant mesothelioma (MM) was
conducted in Casale Monferrato, where the largest Italian
asbestos cement (AC) factory had been operating from 1907 to 1985. In
a previous study we observed a five to seven-fold
increase in the incidence of MM among people living in that city and
never employed in the factory mentioned. The present
study includes cases of MM with histological diagnosis over the
period 1.1.1987-30.6.1993 among residents in the Local
Health Unit (LHU) of Casale Monferrato. Population controls were
randomly extracted from the list of the residents in the
LHU, matched to cases on , date of birth, vital status and date of
death. Cases and controls (or their closest relative) were
interviewed with a standardised questionnaire focusing on asbestos
exposure in the (life-long) residential and occupational
histories and in leisure time activities as well as on occupational
a. |
| The authors briefly reviewed the literature concerning the risk
factors for primary pleural tumors in humans. The results from the
most relevant studies emphasize the fact that the large majority of
mesotheliomas are associated with exposure to asbestos or
asbestiform fibers. Exposure to asbestos is mainly through industrial
use, and mesotheliomas result from occupational,
para-occupational, or environmental exposure. Fibers of crocidolite,
amosite, and chrysotile appear to be, in descending order,
more carcinogenic for pleural tissues. The authors summarize the
available data on consumption of asbestos and
asbestos-based products in Italy. The chrysotile-asbestos mine in
Balangero (Piedmont) stimulated the industrial production of
asbestos-cement; asbestos has been largely sprayed among shipyards
and user for insulating railroad coaches and carriages.
Italy had the greatest consumption of crocidolite in Europe, whi. |
| In order to provide estimates of the accuracy of death certification
of malignant pleural mesothelioma in Italy, the causes of
death of a series of ascertained cases were investigated. The study
included 523 cases of pleural mesothelioma diagnosed in
1984-1988 by 88 hospital departments and clinics. Vital status at 7
May 1990 was ascertained for 92.7% of subjects. The
overall concordance between pathological diagnosis and death
certification was about 75%.
___________________________________________________________
Med Lav 1994 Mar-Apr;85(2):157-60 |
| Latency periods (time intervals elapsing between first exposure to
asbestos and death) were examined in 421 cases of
malignant pleural mesothelioma, diagnosed in the Trieste-Monfalcone
area, Italy. Occupational data were collected from the
patients or from their relatives by personal or telephone interviews.
Routine lung sections were examined for asbestos bodies in
370 cases. Latency periods, calculated in 312 cases, ranged from 14
to 72 years (mean 48.7, median 51). Latency periods
differed significantly from one occupational group to another. Mean
latency periods were 29.6 among insulators, 35.4 among
dock workers, 43.7 in a heterogeneous group defined as various, 46.4
in non-shipbuilding industry workers, 49.4 in shipyard
workers, 51.7 among women with a history of domestic exposure to
asbestos, and 56.2 in people employed in maritime
trades. The ANOVA test indicated a correlation between latency
periods an. |
| All cases of pleural malignant mesothelioma occurring in Tuscany were
collected, backdated to 1980 (to 1970 for the
provinces of Florence and Prato; to 1975 for the provinces of Pisa
and Siena), in order to evaluate the incidence of
occupational exposure to asbestos. The aim was to enhance primary
prevention in those workplaces still at risk nowadays. To
achieve information on the possible occupational, domestic or
environmental exposure, an interview was conducted using a
semi-structured questionnaire. An exposure classification was
produced to focus preventive intervention. This surveillance
system needs to be developed to contribute to epidemiological
research, especially on the effects of low level exposures, and to
primary prevention.
_________________________________________________________
Med Lav 1997 Jul-Aug;88(4):302-9 |
|
